Our researcher has discovered the effect of nanoparticles on DNA damage
Article from Western Caspian University published in SCOPUS - indexed journal of Elmmetric database.
The article “Temporal and dosage impact of magnesium oxide nanoparticles on grass carp: unveiling oxidative stress, DNA damage, and antioxidant suppression”, co-authored by Ayaz Mammadov, Head of the Department of Natural Sciences of Western Caspian University, Ph.D., was published in the Q2-rated Toxicology Mechanisms and Methods journal indexed in Scopus.
The application of magnesium oxide nanoparticles (Mg O NPs) in various nanotechnology-based materials in biomedicine and agriculture has gained significant importance. However, the release of various nanowastes into the aquatic ecosystem is of serious concern.
This research conducted to evaluate the toxic effects of MgO nanoparticles on fish, and oxidative stress biomarkers, antioxidant enzymes, and DNA damage in various visceral organs were determined. The study revealed a significant increase in reactive oxygen species, lipid peroxidation products, DNA damage in multiple visceral organs, and micronucleus formation in fish erythrocytes, depending on dose and time.